Mapping Interindividual Variation in the Aging Connectome (MIVAC)

Publication:

MacKay-Brandt A, Gazes Y, Garcia-Barnett D, Grebe L, Ripley O, Gan KX, Trautman KT, Kramer M, Breland M, Tobe R, Franco A, Gabbay V, Milham M, Colcombe S. An open, longitudinal resource for mapping interindividual variation in the aging connectome. medRxiv [Preprint]. 2025 Oct 13:2025.10.10.25337774. doi: 10.1101/2025.10.10.25337774. PMID: 41282656; PMCID: PMC12633132.

MIVAC Static Phenotypic Dataset

For access to the static version of the dataset used in “Mapping interindividual variation in the aging connectome” data descriptor paper: upon full execution of the DUA, please contact our support team at: RocklandSample.Enduser@NKI.rfmh.org, Subject line “MIVAC descriptor paper dataset”.

Neuroimaging Data

Neuroimaging data are available for separate download in the AWS S3 bucket in BIDS format (see instructions); the corresponding AWS path to the MRI images for each participant/visit are specified as variables in the phenotypic data with custom_ID as the linking variable.

Documentation

  • Detailed information on all variables used in this manuscript is provided in the variables_used table, which lists each variable and the associated instrument file and column name(s) used to derive each variable.
  • Codebook and instrument-specific data dictionaries are available here.
  • Scripts used to compute summary scores: PSQI and PENN_CNP.
  • Description of diffusion MRI processing pipeline in QSIprep and QSIRecon are downloadable here.